Backing the New Orleans Saints to cover the low spread on FanDuel Sportsbook is the most logical wager for the game lines market. This matchup hinges entirely on how both coaching staffs are managing their depth charts following intense joint practice sessions in Westlake Village. New Orleans head coach Kellen Moore announced that his primary starting unit will sit out this exhibition game entirely. The starting group already logged heavy repetitions during mid-week drills.

This opens up a massive showcase for the Saints’ highly capable backup quarterback rotation. Former first-round pick Zach Wilson is expected to command the bulk of the early snaps after delivering a highly productive performance in the preseason opener. Wilson’s extensive regular-season starting experience provides a severe talent advantage against secondary defensive schemes. Given his ability to move the chains against deep-roster bubble players, the Saints are positioned well to clear a short under-the-field-goal line.

Los Angeles Rams Team Total Under 16.5 (-110)

Instead of relying on volatile fourth-quarter moneyline swings, targeting the Los Angeles Rams’ team total under provides a much safer angle. Head coach Sean McVay is mirroring the Saints’ conservative approach by resting elite starters like Matthew Stafford and Puka Nacua. This leaves the Rams’ offensive production in the hands of rookie signal-caller Ty Simpson and a collection of undrafted free agents.

While Simpson showed flashes of potential against the Kansas City Chiefs in Week 1, he faces a far more disciplined defensive depth chart this week. The Saints’ secondary depth performed exceptionally well during joint practices, consistently suffocating backup timing routes. Without top-tier playmakers to bail out broken plays, the Rams’ reserve offense will likely struggle with consistency. Expect long, run-heavy drives that ultimately stall out around midfield, keeping Los Angeles under this scoring threshold.

Game Total Under 37.5 (-110)

The smartest play on the entire board is the under on the 37.5 total game points line. Preseason Week 2 matchups are historically excellent spots for defensive execution, especially when both teams spent the preceding 48 hours hitting each other in controlled practice environments.

Coaching staffs often use the live game broadcast to evaluate blocking assignments, bubble-roster special teams players, and baseline tackling rather than opening up their actual regular-season playbooks. With basic, vanilla play-calling dominating the script on both sides, explosive downfield plays will be scarce. A heavy rotation of ground plays from backup running backs like Kendre Miller and Dean Connors will keep the clock moving constantly, ensuring a low-scoring affair.