Backing the Indianapolis Colts to cover the spread at home on FanDuel Sportsbook is the most logical wager for this game lines market. Head coach Kevin Stefanski has already announced that Atlanta will completely rest its primary starters for this matchup, relying entirely on joint practice sessions for their first-team repetitions.

This means the Falcons will completely sit starting quarterback Tua Tagovailoa, leaving backup duties to Cooper Rush and Jack Strand. Furthermore, rookie Michael Penix Jr. is still restricted to individual drills and is entirely unavailable for live 11-on-11 contact. Because Indianapolis boasts much deeper quarterback stability and home-field execution, they are primed to pull away against Atlanta’s depth pieces and comfortably clear a small hook.

Atlanta Falcons Team Total Under 16.5 (-115)

Instead of targeting a potentially volatile game-winner market, betting against Atlanta’s offensive depth chart offers a much safer approach. In their preseason opener, the Falcons struggled significantly to establish a rhythm or move the chains efficiently.

With Tagovailoa on the bench and a highly restricted quarterback rotation, Atlanta’s offensive rhythm will suffer. Their offensive line struggled heavily with consistency during joint practice sessions against the Colts’ primary defensive front. Without top tier skill players like Drake London on the field to create space, Atlanta will rely heavily on an unproven running game. This heavily conservative play-calling script should severely limit their red zone trips.

Game Total Under 36.5 (-104)

The smartest overall bet on the board is the under on the 36.5 total point line. Preseason Week 2 is a notorious dead zone for offensive efficiency, especially after two teams spend consecutive days hitting each other in high-tempo joint practices.

Coaching staffs use the actual game tape to evaluate baseline roster cuts rather than opening up their playbook or showing off intricate schemes. Because both sides will run vanilla concepts and keep the ball on the ground to accelerate the clock, explosive downfield plays will be virtually nonexistent. Expect a defensive slugfest that finishes well short of the closing numbers.